Secretariat Großhansdorf

Irene Joraszik

Sieker Landstraße 2
22927 Großhansdorf
Phone: +49 4102 696 0
Fax: +49 4102 696 200
fg@thuenen.de

Location manager Waldsieversdorf

  • Volker Schneck

Secretariat Waldsieversdorf

Stefanie Mordau

Eberswalder Chaussee 3a
15377 Waldsieversdorf
Phone: +49 33433 157 0
Fax: +49 33433 157 199
fg-ws@thuenen.de


Biosafety of transgenic trees

Project

 (c)

 
Gene transfer and biosafety of biotechnologically grown trees

Following the year 2008 transgenic trees to be foreseen for non-commercial field releases as well as for commercial applications shouldn't contain any antibiotic resistance gene marker. Further, it has been claimed in particular for trees that the foreign genes introduced into tree genomes should be positioned at genomic locations which has been found suitable for integration of forest genes. In this project the possibilities for a targeted transfer of transgenes as well the elimination of marke

Background and Objective

In this project the possibilities for a targeted transfer of transgenes as well the elimination of marker genes will be studied. In frame of a biological biosafety research are these investigations very important in order to assess possible risks following the practical application of such systems.

Approach

This project is based on preliminary with using recombination systems, which has been successfully tested in annual plants. Also for aspen it has been shown, that the recombination systems Cre/lox as well FLP/FRT work well. For risk assessment studies it has to be analysed whether pleiotropic effects can be observed in transgenic trees carrying recombination systems.

Preliminary Results

This project is based on preliminary with using recombination systems, which has been successfully tested in annual plants. Also for aspen it has been shown, that the recombination systems Cre/lox as well FLP/FRT work well. For risk assessment studies it has to be analysed whether pleiotropic effects can be observed in transgenic trees carrying recombination systems.

Thünen-Contact


Involved Thünen-Partners


Duration

3.2004 - 5.2024

More Information

Projekt type:
Project status: ongoing

Publications

Results 11 - 16 of 16

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  1. Bentley AR, Jensen EF, Mackey IJ, Hönicka H, Fladung M, Hori K, Yano M, Mullet JE, Armstead IP, Hayes C, Thorogood D, Lovatt A, Morris R, Pullen N, Mutasa-Göttgens ES, Cockram J (2013) Chapter 1 : Flowering time. In: Kole C (ed) Genomics and breeding for climate-resilient crops : Vol. 2 target traits . Berlin: Springer, pp 1-66
  2. Fladung M, Hönicka H, Ahuja MR (2013) Genomic stability and long-term transgene expression in poplar. Transgenic Res 22(6):1167-1178, DOI:10.1007/s11248-013-9719-2
  3. Hönicka H, Lehnhardt D, Polak O, Fladung M (2012) Early flowering and genetic containment studies in transgenic poplar. iForest 5:138-146, DOI:10.3832/ifor0621-005
  4. Fladung M, Altosaar I, Bartsch D, Baucher M, Boscaleri F, Gallardo F, Häggman H, Hönicka H, Nielsen K, Paffetti D, Seguin A, Stotzky G, Vettori C (2012) European discussion forum on transgenic tree biosafety. Nature Biotechnol 30(1):37-38, DOI:10.1038/nbt.2078
  5. Fladung M, Hönicka H (2012) Fifteen years of forest tree biosafety research in Germany. iForest 5:126-130, DOI:10.3832/ifor0619-005
  6. Knoop M von, Fladung M (2012) Stadtbäume als Ergänzung des Biomasseaufkommens? : eine Herausforderung für die Gentechnik. AFZ Wald 67(12):16-19
    pdf document (limited accessibility) 281 kb

Results 11 - 16 of 16

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