Investigation of PF1022A producing microorganisms living as saprophytes and endophytes in broadleaved and conifer forest trees
Fungal strains from woody material of woodland and forest tree species of natural forest sites could be identified as producers of the cyclic octadepsipeptide PF1022A and related compounds. These metabolites possess anthelmintic / nematicidal activity. All fungal strains belong to group of Xylariaceae. The strains identified as producers during the last project have to improve regarding the efficacy of metabolite production. Additionally, some other derivates were detected from single isolates. Further Aim is the selection of novel strains producing metabolites with anthelmintic character.
Collection and identification of PF1022A producing fungal strains
evidence of anthelmintic compounds
11.2011 - 6.2014
Project status: finished