Prevention is crucial to maintain herd health and welfare. In all parts of the environment behavioral and biological needs of the animals has to be taken into account in order reduce stress. On the other hand herd management and hygiene are needed to reduce infection prevalence and not to overstraine the adaptability of farm animals in the farm environment. Therefore the aim of the research is to focus on the development and enhancement of preventive management concepts to enhance animal health and welfare under practical conditions. Furthermore the aim is to focus on the identification and validation of animal based indicators to assess health and welfare of livestock on-farm. Epidemiologic topics such as the analysis of risk factors for certain production diseases are also under study.